Mechanical stimulus is the driving force for numerous physiological processes including pain sensation, hearing, and blood pressure regulation2. Piezo1 and …
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In Focus: 5-HT3 Receptors
5-HT (5-hydroxytryptamine, serotonin) is one of the most versatile neurotransmitters. It signals in part through 5-HT3 receptors which belong to …
By Alomone Labs
Continue reading In Focus: Chemokine Receptors
Chemokines (CHEMOtactic cytoKINES) are an important subgroup of the inflammatory cytokine family. More than fifty chemokines are expressed in mammalian …
By Alomone Labs
Continue reading In Focus: Connexin and Pannexin Gap Junction Channels
Gap junctions are usually found in clusters and enable intercellular communication by allowing the passage of small molecules between cells2. …
By Alomone Labs
Continue reading In Focus: Ionotropic Glutamate Receptors
The excitatory effects of glutamate (the major excitatory neurotransmitter) are mediated by the activation of ionotropic and metabotropic receptors. These …
By Alomone Labs
Continue reading In Focus: NCX Exchangers
Ca2+ has proven to be a universal signaling molecule in excitable and nonexcitable cells. However, being that its intracellular concentration …
By Alomone Labs
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