The erg or KV11 (according to the new nomenclature) is a subfamily of the voltage dependent K+ channel superfamily and includes …
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Articles
The Sexiest Channels Alive: The Role of Ion Channels in Penile Erection
Penile erection is a spinal reflex that involves integration of tactile, olfactory, visual and auditory inputs in the central nervous …
Continue readingIon Channel Modulation by G-Protein Coupled Receptors
The G-protein coupled receptors (GPCRs) are the largest and most versatile protein family in the mammalian genome. They interact with …
Continue readingIon Channels and Oxygen Sensing in the Carotid Body
Oxygen is an absolute requirement of all mammalian cells. Practically every cell is able to sense a decrease in oxygen …
Continue readingThe Role of Ion Channels in Neurodegeneration
Neurodegenerative diseases take an enormous toll on society as well as on individuals. Very limited treatments for these diseases exist, …
Continue readingThe Transient Receptor Potential Superfamily: Antibodies in Action
The transient receptor potential (TRP) superfamily, one of the largest ion channel families, consists of a diverse group of proteins. …
Continue readingK+ Channels in Cardiomyocytes
The contribution and importance of K+ channels to the normal activity of the heart is best exemplified by disturbances in …
Continue readingThe Involvement of Ion Channels in Cell Proliferation
The control of cell proliferation involves diverse signaling pathways, growth factors, and receptors. The involvement of ion channels in this …
Continue readingTripping Over TRPC
The canonical transient receptor potential channels (TRPCs) are non-selective cation channels that are expressed in a variety of multicellular organisms …
Continue readingIonotrophic ATP (P2X) Receptors
P2X receptors are surface membrane ligand-gated channel proteins that rapidly translate extracellular ATP elevation into an intracellular Ca2+ surge which …
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