Ion Channels in Pain

• Jingzhaotoxin-II

  An Activator of Na_V Channels

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  Cat # STJ-150

  MW 3561 Da

  Target Na_V Na⁺ Channels

  More info

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• Ligustilide

  An Activator of TRPA1 Channels

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  Cat # L-170

  Source Natural

  MW 190.2

  Target TRPA1 channels

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• (-)-Nicotine ditartrate

  An Agonist of nAChR

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  Cat # N-175

  Source Synthetic

  MW 462.4

  Target nAChR

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• NMDA

  An NMDA Receptor Agonist

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  Cat # N-170

  Source Synthetic

  MW 147.1

  Target NMDA receptors

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• Nonivamide

  A Potent Activator of TRPV1 Channels

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  Cat # N-220

  Source Synthetic

  MW 293.4

  Target TRPV1 channels

  More info

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• NS-309

  A Positive Modulator of Small- and Intermediate-Conductance K_Ca Channels

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  Cat # N-180

  Source Synthetic

  MW 231.04

  Target K_Ca2 and K_Ca3.1 K⁺ channels

  More info

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• NS-1643

  An Opener of K_V11.1 and KCNQ2 K⁺ Channels

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  Cat # N-115

  Source Synthetic

  MW 380.2

  Target K_V11.1, KCNQ2 K⁺ channels

  More info

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• OLDA

  An Activator of TRPV1 Channel

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  Cat # O-120

  Source Synthetic

  MW 417.6

  Target TRPV1 channels

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• Olvanil

  An Activator of TRPV1 Channel and Cannabinoid Receptors

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  Cat # O-115

  Source Synthetic

  MW 417.6

  Target TRPV1 channels, Cannabinoid receptors

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• Ononetin

  A Potent TRPM3 Channel Blocker and a TRPA1 Channel Activator

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  Cat # O-135

  Source Synthetic

  MW 258.27

  Target TRPM3, TRPA1 channels

  More info

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• Optovin

  A Novel Photosensitive Activator of TRPA1 Channel

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  Cat # O-140

  Source Synthetic

  MW 315.41

  Target TRPA1 channels

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• Palvanil

  An Activator of TRPV1 Channels

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  Cat # P-205

  Source Synthetic

  MW 391.3

  Target TRPV1 channels

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• PNU 282987

  Selective Agonist of α7 nAChR

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  Cat # P-110

  Source Synthetic

  MW 264.75

  Target α7 nAChR

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• QO-40

  An Opener of KCNQ Channels

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  Cat # Q-265

  Source Synthetic

  MW 377.8

  Target KCNQ channels

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• Resiniferatoxin

  A Potent and Selective Activator of TRPV1 Channel

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  Cat # R-400

  Source Natural

  MW 628.72

  Target TRPV1 channels

  More info

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• Retigabine

  A Potent and Selective Modulator of KCNQ Channels

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  Cat # R-100

  Source Synthetic

  MW 303.3

  Target KCNQ2, KCNQ3, and KCNQ4 K⁺ channels

  More info

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• Retigabine dihydrochloride

  A Potent and Selective Modulator of KCNQ Channels

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  Cat # R-101

  Source Synthetic

  MW 376.2

  Target KCNQ2, KCNQ3, KCNQ4 K⁺ channels

  More info

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• SKA-31

  A Potent Activator of K_Ca3.1 and K_Ca2 Channels and a Blocker of TRPM7 Channel 

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  Cat # S-120

  Source Synthetic

  MW 200.2

  Target K_Ca2, K_Ca3.1, TRPM7 channels

  More info

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• Tf2 Toxin

  An Opener of Na_V1.3 and Na_V1.9 Channels

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  Cat # STT-050

  MW 6954 Da

  Target Na_V1.3, Na_V1.9 channels

  More info

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• Tracazolate hydrochloride

  A Modulator of GABA(A) Receptors

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  Cat # T-230

  Source Synthetic

  MW 340.85

  Target GABA(A) receptors

  More info

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