Ion Channels in Pain

• BomoTx Toxin

  A Somatosensory, Pain Inducing Neuron Stimulator, Indirect P2X2/P2X3 Receptor Agonist

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  Cat # NTB-200

  MW 13834 Da

  Target P2X2/P2X3 receptors

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• Cannabichromene

  An Activator of TRPA1 Channels and an Antagonist of Cannabinoid Receptor 1 and TRPM8 Channels

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  Cat # C-315

  Source Synthetic

  MW 314.5

  Target TRPA1, TRPM8 channels, Cannabinoid receptor 1

  More info

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• Capsaicin

  A Powerful TRPV1 Agonist

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  Cat # C-125

  Source Synthetic

  MW 305.4

  Target TRPV1 channels

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• Capsiate

  A TRPA1 and TRPV1 Channel Activator

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  Cat # C-255

  Source Natural

  MW 306.4

  Target TRPA1, TRPV1 channels

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• CGS 20625

  A Partial Agonist of GABA(A) Receptors

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  Cat # C-390

  Source Synthetic

  MW 309.36

  Target GABA(A) receptors

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• Chlormethiazole hydrochloride

  A Positive Modulator of GABA(A) and Glycine Receptors

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  Cat # C-360

  Source Synthetic

  MW 198.11

  Target GABA(A), Glycine receptors

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• Cono AIVGRPRF-amide

  A Specific Potentiator of ASIC3 Channel

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  Cat # STC-174

  MW 914 Da

  Target ASIC3 channel

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• Cono RPRF-amide

  A Specific Potentiator of ASIC3 Channel

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  Cat # STC-170

  MW 574 Da

  Target ASIC3 channel

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• Cono VGRPRF-amide

  A Specific Potentiator of ASIC3 Channel

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  Cat # STC-172

  MW 730 Da

  Target ASIC3 channel

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• Curcumin

  An Activator of TRPA1 Channels

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  Cat # C-230

  Source Natural

  MW 368.4

  Target TRPA1 channels

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• (-)-Cytisine

  A nAChR Agonist and a Partial Agonist of β2 Subunit

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  Cat # C-130

  Source Synthetic

  MW 190.2

  Target nAChR

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• DMAB-anabaseine dihydrochloride

  Antagonist or Partial Agonist of nAChR

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  Cat # D-110

  Source Synthetic

  MW 364.3

  Target nAChR

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• Ganaxolone

  A Selective Positive Modulator of GABA(A) Receptors

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  Cat # G-120

  Source Synthetic

  MW 332.5

  Target GABA(A) receptors

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• GMQ

  An ASIC Channel Modulator and an ASIC3 Channel Opener

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  Cat # G-130

  Source Synthetic

  MW 201.2

  Target ASIC1a, ASIC2, ASIC3

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• GMQ hydrochloride

  An ASIC Channel Modulator and an ASIC3 Channel Opener

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  Cat # G-165

  Source Synthetic

  MW 237.1

  Target ASIC1a, ASIC2, ASIC3

  More info

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• GV-58

  An Activator of Ca_V2.2 and Ca_V2.1 Ca²⁺ Channels

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  Cat # G-140

  Source Synthetic

  MW 374.2

  Target Ca_V2.1, Ca_V2.2 Ca²⁺ channels

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• Hm3a Toxin

  A Highly Potent ASIC1a Blocker and ASIC1b Activator

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  Cat # STH-250

  MW 4287.1 Da

  Target ASIC1a and ASIC1b

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• ICA-27243

  A Potent and Selective Opener of KCNQ2 and KCNQ3 K⁺ Channels

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  Cat # I-130

  Source Synthetic

  MW 268.64

  Target KCNQ2, KCNQ3 K⁺ channels

  More info

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• ICA-110381

  An Opener of KCNQ Channels

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  Cat # I-160

  Source Synthetic

  MW 267.1

  Target KCNQ channels

  More info

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• Isoguvacine hydrochloride

  An Agonist of GABA(A) Receptors

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  Cat # I-185

  Source Synthetic

  MW 163.6

  Target GABA(A) receptors

  More info

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* See product page