Flexibility. Specificity. Satisfaction.

Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

Connexins (Cx) include 21 integral membrane proteins belonging to this family and form homomeric or heteromeric hexamers generally termed connexons or hemi-channels. In turn, these hemi-channels further assemble in a head-to-head manner, thus forming gap junction channels. Connexins are ubiquitously expressed and their activity is regulated at the expression level and by post-translational modifications. Due to their important roles, mutations in connexins are linked to a number of diseases such as neurodegenerative disorders, skin diseases and developmental abnormalities.