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Home › Products › Neural Signaling › Ca2+ Signaling › ASIC/ENaC/Degenerin Family › Acid-Sensing Ion Channels (ASIC) › Antibodies to ASICs

Acid-Sensing Ion Channels (ASIC)

Antibodies to ASICs

ASIC channels belong to the ENaC/Degenerin superfamily and are proton-gated ion channels which are not voltage-dependent. Six different genes encode the different ASIC subunits and splice variants: ASIC1a, ASIC1b, ASIC2a, ASIC2b, ASIC3 and ASIC4. The topology of ASIC channels is predicted on the basis of that of ENaCs. However, different computational programs have depicted different structures for the ASIC channels.

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