Ion Channels in Epilepsy

• µ-Conotoxin BuIIIB

  A Blocker of Na_V1.4 and Na_V1.3 and Na_V1.2 Na⁺ Channels

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  Cat # STC-661

  MW 2764 Da

  Target Na_V1.2, Na_V1.3 and Na_V1.4 Na⁺ channels

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• µ-Conotoxin CnIIIC

  A Blocker of Na_V Channels and an Antagonist of nAChRs

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  Cat # STC-640

  MW 2376 Da

  Target Na_V channels, α3/β2 nAChR

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• µ-Conotoxin KIIIA

  A Potent Blocker of Mammalian TTX-Sensitive Na_V1 Channels

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  Cat # C-280

  MW 1883 Da

  Target TTX-sensitive Na⁺ channels

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• µ-Conotoxin PIIIA

  A Potent Blocker of Na_V1.2, Na_V1.4 and Na_V1.7 Na⁺ Channels

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  Cat # STC-400

  MW 2604 Da

  Target Various Na_V channels

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• µ-Conotoxin SIIIA

  A Blocker of TTX-Sensitive Na_V1.2, Na_V1.3 and Na_V1.4 Voltage-Gated Na⁺ Channels

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  Cat # STC-450

  MW 2207 Da

  Target Na_V1.2, Na_V1.3, Na_V1.4 Na⁺ channels

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• ω-Agatoxin IVA

  A Blocker of P/Q-Type Ca_V Channels

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  Cat # STA-500

  MW 5202 Da

  Target P-type Ca²⁺ channels

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• ω-Agatoxin TK

  A Blocker of P/Q-Type Ca_V Channels

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  Cat # STA-530

  MW 5273 Da

  Target P-type and Q-type Ca²⁺ channels

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• ω-Conotoxin CVIB

  A Blocker of N-, P/Q-Type Ca²⁺ Channels

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  Cat # STC-410

  MW 2710 Da

  Target N-, P/Q-type Ca²⁺ channels

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• ω-Conotoxin CVIC

  A Blocker of N-, P/Q-Type Ca²⁺ Channels

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  Cat # STC-420

  MW 2783 Da

  Target N-, P/Q-type channels

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• ω-Conotoxin MVIIC

  A Blocker of Presynaptic Ca_V (N- and P/Q-Type) Channels

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  Cat # C-150

  MW 2750 Da

  Target N-type and P/Q-type Ca²⁺ channels

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• ω-Conotoxin MVIID

  A Blocker of N- and P-Type Ca_V Channels 

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  Cat # STC-751

  MW 2695 Da

  Target N-, P-type Ca²⁺ channels

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• Amentoflavone

  A Negative Allosteric Modulator of GABA(A) Receptors

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  Cat # A-165

  Source Natural

  MW 538.46

  Target GABA(A) receptors

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• AmmTx3 Toxin

  A Blocker of A-Type K⁺ Channels

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  Cat # STA-305

  MW 3822 Da

  Target K_V4 K⁺ channels

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• Apamin

  A Blocker of Small Conductance Ca²⁺-Activated K⁺ Channels (SK Type)

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  Cat # STA-200

  MW 2028 Da

  Target K_Ca2 K⁺ channels

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• Apamin-Biotin

  A Blocker of Small Conductance Ca²⁺-Activated K⁺ Channels (SK Type) Conjugated to Biotin

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  Cat # STA-200-B

  MW 2367 Da

  Target K_Ca2 K⁺ channels

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• Arcaine sulfate

  An Antagonist of NMDA Receptors

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  Cat # A-285

  Source Synthetic

  MW 270.31

  Target NMDA receptors

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• L-Ascorbic acid

  A Blocker of T-Type Ca_V Channels

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  Cat # L-140

  Source Synthetic

  MW 176.1

  Target T-type Ca²⁺ channels

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• BDS-I

  A Blocker of K_V3 Channels and a Modulator of Na_V Channels

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  Cat # STB-400

  MW 4708 Da

  Target K_V3 K⁺ channels, Na_V Na⁺ channels

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• BDS-II

  A Blocker of K_V3 Channels and a Modulator of Na_V Channels

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  Cat # B-450

  MW 4776 Da

  Target K_V3 K⁺ channels, Na_V Na⁺ channels

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• Benidipine hydrochloride

  A Dihydropyridine Blocker of Voltage-Gated Ca²⁺ Channels

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  Cat # B-120

  Source Synthetic

  MW 542

  Target Ca_V1, Ca_V3 Ca²⁺ channels

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