Ion Channels in Epilepsy

• Pterinotoxin-1

  A Novel Blocker of Na_V1.3, Na_V1.7, and Na_V1.8 Voltage-Gated Na⁺ Channels

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  Cat # STT-100

  MW 3970 Da

  Target Na_V channels

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  • 

• Pterinotoxin-2

  A Blocker of Na_V1.3 and Na_V1.7 Na⁺ Channels

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  Cat # STT-150

  MW 3637 Da

  Target Na_V1.3, Na_V1.7 Na⁺ channels

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• Pyrrolopyrimidine 48

  A Blocker of Na_V1.7 and Na_V1.5 Channel

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  Cat # P-275

  Source Synthetic

  MW 385.46

  Target Na_V1.7, Na_V1.5 channels

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• QX-222 chloride

  A Blocker of Na_V Channels

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  Cat # Q-200

  Source Synthetic

  MW 256.77 (as net anhydrous)

  Target Various Na_V Na⁺ channels

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• QX-314 bromide

  A Local Anesthetic Blocker of Some Na_V Channels

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  Cat # Q-100

  Source Synthetic

  MW 343.3

  Target Various Na_V  Na⁺ channels

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  • 

• QX-314 chloride

  A Local Anesthetic Blocker of Na_V Channels

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  Cat # Q-150

  Source Synthetic

  MW 298.85

  Target Various Na_V Na⁺ channels

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  • 

• Ralfinamide mesylate

  A Use-Dependent Blocker of Na_V Channels

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  Cat # R-105

  Source Synthetic

  MW 398.5

  Target Na_V Na+ channels

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• Ro 8-4304 hydrochloride

  A Selective Antagonist of NMDA Receptors

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  Cat # R-165

  Source Synthetic

  MW 406.88

  Target NMDA receptors

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• Ro 25-6981 maleate

  A Potent and Selective Antagonist of GluN2B-Containing NMDA Receptors

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  Cat # R-180

  Source Synthetic

  MW 455.55

  Target GluN2B

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• RY796

  A Blocker of K_V2 Channels

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  Cat # R-160

  Source Synthetic

  MW 353.5

  Target K_V2 channels

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• Scyllatoxin

  A Potent Blocker of K_Ca2 (SK) K⁺ Channels

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  Cat # STS-370

  MW 3423 Da

  Target K_Ca2 K⁺ channels

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  • 

• SKF 96365 hydrochloride

  A Blocker of Ca_V3 and TRPC channels and STIM1

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  Cat # S-175

  Source Synthetic

  MW 402.9

  Target Ca_V3 channels, TRPC, STIM1

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• SNX-482

  A Blocker of Ca_V2.3 and K_V4.3 Channels

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  Cat # RTS-500

  MW 4495 Da

  Target Ca_V2.3, Ca_V2.1, K_V4.2, K_V4.3 channels

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• Spinoxin

  A Potent Blocker of K_V1.2 and K_V1.3 Channels

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  Cat # STS-500

  MW 3701.2 Da

  Target K_V1.2, K_V1.3 channels

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• SsTx Toxin

  A Blocker of KCNQ and K_V1.3 Channels

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  Cat # STS-700

  MW 6018 Da

  Target KCNQ1, KCNQ2, KCNQ4, KCNQ5, K_V1.3 channels

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• ShK (Stichodactyla Toxin)

  A Blocker of K_V Channels

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  Cat # STS-400

  MW 4055 Da

  Target Various K_V K⁺ channels

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  • 

• Stichodactyla Toxin-ATTO Fluor-590

  Fluorescent ShK Conjugate for Sensitive Detection of K_V Channels

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  Cat # STS-400-AR

  MW ~4627 Da

  Target K_V1.1, K_V1.3, K_V1.4, K_V1.6 channels

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  • 

• Stichodactyla Toxin-Biotin

  Biotinylated ShK Conjugate for Sensitive Detection of K_V Channels

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  Cat # STS-400-B

  MW 4563 Da

  Target K_V1.1, K_V1.3, K_V1.4, K_V1.6 channels

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• Stromatoxin-1

  A Potent Blocker of K_V2.1, K_V2.2, K_V4.2 and K_V9.3 Channels

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  Cat # STS-350

  MW 3792 Da

  Target Various K_V channels

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  • 

• Tamapin

  A Blocker of K_Ca2 Channels

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  Cat # STT-400

  MW 3458.16 Da

  Target K_Ca2 K⁺ channels

  More info

  • 

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