Ion Channels in Pain

• ProTx-I

  A Blocker of Na_V, Ca_V3.1, K_V2.1 and TRPA1 Channels

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  Cat # STP-400

  MW 3988 Da

  Target Na_V, Ca_V3.1, K_V2.1, TRPA1 channels

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• ProTx-II

  A Blocker of Na_V1.7 and Na_V1.5 Channels and Some T-Type Ca²⁺ Channels

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  Cat # STP-100

  MW 3826.6 Da

  Target Na_V channels and T-type Ca²⁺ channels

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• ProTx-II-Biotin

  A Blocker of Na_V1.7 and Na_V1.5 Channels and some T-Type Ca²⁺ Channels Conjugated to Biotin

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  Cat # STP-100-B

  MW 4053 Da

  Target Na_V Na⁺ channels and T-type Ca²⁺ channels

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• ProTx-III

  A Potent Blocker of Na_V1.7 Channels

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  Cat # STP-150

  MW 3802 Da

  Target Na_V1.7 channels

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• Psalmotoxin-1

  A Potent Blocker of ASIC1a Channels

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  Cat # STP-200

  MW 4689.5 Da

  Target ASIC1a channels

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• Pyrrolopyrimidine 48

  A Blocker of Na_V1.7 and Na_V1.5 Channel

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  Cat # P-275

  Source Synthetic

  MW 385.46

  Target Na_V1.7, Na_V1.5 channels

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• RO-3

  A Potent and Selective Antagonist of P2X3 and P2X2/3 Receptors

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  Cat # R-190

  Source Synthetic

  MW 302.37

  Target P2X3 receptors

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• Ro 25-6981 maleate

  A Potent and Selective Antagonist of GluN2B-Containing NMDA Receptors

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  Cat # R-180

  Source Synthetic

  MW 455.55

  Target GluN2B

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• Ro-51

  A Highly Potent and Selective Antagonist of P2X3 and P2X2/3 Receptors

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  Cat # R-195

  Source Synthetic

  MW 474.29

  Target P2X3 receptors

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• SB-366791

  A Specific and Potent TRPV1 Blocker

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  Cat # S-180

  Source Synthetic

  MW 287.7

  Target TRPV1 channels

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• SB-705498

  A Blocker of TRPV1 Channels

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  Cat # S-160

  Source Synthetic

  MW 428.05

  Target TRPV1 channels

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• Scyllatoxin

  A Potent Blocker of K_Ca2 (SK) K⁺ Channels

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  Cat # STS-370

  MW 3423 Da

  Target K_Ca2 K⁺ channels

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• sFTX-3.3

  A Blocker of P-Type Ca_V Channels

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  Cat # F-130

  Source Synthetic

  MW 287.4

  Target P-type Ca²⁺ channels

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• SKF 96365 hydrochloride

  A Blocker of Ca_V3 and TRPC channels and STIM1

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  Cat # S-175

  Source Synthetic

  MW 402.9

  Target Ca_V3 channels, TRPC, STIM1

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• SNX-482

  A Blocker of Ca_V2.3 and K_V4.3 Channels

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  Cat # RTS-500

  MW 4495 Da

  Target Ca_V2.3, Ca_V2.1, K_V4.2, K_V4.3 channels

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• Spinoxin

  A Potent Blocker of K_V1.2 and K_V1.3 Channels

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  Cat # STS-500

  MW 3701.2 Da

  Target K_V1.2, K_V1.3 channels

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• ShK (Stichodactyla Toxin)

  A Blocker of K_V Channels

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  Cat # STS-400

  MW 4055 Da

  Target Various K_V K⁺ channels

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• Stichodactyla Toxin-ATTO Fluor-590

  Fluorescent ShK Conjugate for Sensitive Detection of K_V Channels

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  Cat # STS-400-AR

  MW ~4627 Da

  Target K_V1.1, K_V1.3, K_V1.4, K_V1.6 channels

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• Tamapin

  A Blocker of K_Ca2 Channels

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  Cat # STT-400

  MW 3458.16 Da

  Target K_Ca2 K⁺ channels

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• TCN 213

  An Antagonist of NMDA Receptors

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  Cat # T-215

  Source Synthetic

  MW 376.54

  Target NMDA receptors

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