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ShK-235
A Potent Blocker of KV1.3 Channels
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Vm24 Toxin
A Potent and Specific Blocker of Kv1.3 Channel
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Displaying 1 to 2 products (out of 2 products)
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K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. KV channels fall into one of the two classical categories of delayed rectifier (DR) and A-type. Delayed rectifier was the original name attributed to voltage-dependent K+ channels due to their delayed activation in squid giant axons. A-type channels are low voltage-activated, fast inactivating (therefore, transient) K+ channels. Specific KV toxins are often used to dissect the particular contribution of different subunits to native currents.