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Anti-Endothelin Receptor A (extracellular) Antibody
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Anti-Endothelin Receptor B (extracellular) Antibody
A rabbit polyclonal antibody to Endothelin Receptor B (extracellular)
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Alomone Labs FITC-conjugated extracellular antibodies offer you significant advantages. Skip cell permeabilization/fixation.
NOW you can conduct flow cytometry using live cells in ONE single step.
These novel antibodies save you valuable time and resources, while empowering your research results.
Benefits:
✓ Developed for flow cytometry (FACS)
✓ Tested with appropriate isotype control
✓ No need for secondary antibodies
✓ Conjugated to “extracellular” antibodies
✓ Cell-surface detection of proteins
✓ Permeabilization & cell fixation not required
✓ Time saving
Within our antibody portfolio, we gladly take on special requests for customized antibody labeling/conjugation.
Endothelin, a 21–amino acid peptide, has potent and sustained vasoconstrictive effects on vascular smooth muscle both in vivo and in vitro and is found in three different isoforms. ET-1 binds and activates two G-protein coupled receptors: ET-A and ET-B. While the former has been attributed to vasoconstriction, the role of ET-B depends mostly on its location; on one hand it could promote vasoconstriction and on the other stimulate nitric oxide (NO) release -a known vasodilator.