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Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

L-type Ca²⁺ channels include four different isoforms of the α1 pore-forming subunit: Ca_V1.1, Ca_V1.2, Ca_V1.3 and Ca_V1.4. Their expression is detected in muscle, heart, retina and neurons where they play important roles in muscle contraction, hormone secretion, neuronal excitability and gene expression.