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Antibodies raised in guinea pig can be used with antibodies raised in mouse, rabbit, goat, etc. in complex immunostaining or immunoprecipitation protocols.

Four members of the TRPV family have been described as a thermosensitive ion channels (TRPV1 to TRPV4). Each channel exhibits distinct thermal activation thresholds ranging from noxious cold (<17°C) to noxious heat (>52°C).TRPV1 has many activators among them heat, protons, vanilloids like capsaicin, resiniferatoxin (RTX) and lipids. This channel is associated with tissue injury and inflammation.