Alomone Labs has developed two innovative platforms for studying protein-protein interaction and/or protein co-localization in complex immunostaining or immunoprecipitation protocols:

ATTO-Conjugated Antibodies: These antibodies can be used in immunohistochemistry (IHC) and immunocytochemistry (ICC) with same species antibodies.

Save time and resources with ONE antibody.

Benefits of immunostaining with ATTO-conjugated antibodies:
✓ Direct immuno-fluorescence
✓ Secondary antibodies are not necessary
✓ Ideal for immuno-colocalization with same species/host antibodies

More on ATTO dyes

Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.

Voltage-dependent Ca²⁺ channels (Ca_V) form an important route for Ca²⁺ entry into cells, upon deviations from the cells’ resting membrane potential. There are ten Ca_V α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The Ca_V1 subfamily includes four genes which encode the L-type channels, the Ca_V3 subfamily includes three genes encoding the T-type channels and the Ca_V2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.