The G-protein coupled receptors (GPCRs) are the largest and most versatile protein family in the mammalian genome. They interact with …
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Issue No. 21
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The Sexiest Channels Alive: The Role of Ion Channels in Penile Erection
Penile erection is a spinal reflex that involves integration of tactile, olfactory, visual and auditory inputs in the central nervous …
Continue readingThe ether-a-go-go Related Gene (erg) Voltage-Gated K+ Channels: A Common Structure With Uncommon Characteristics
The erg or KV11 (according to the new nomenclature) is a subfamily of the voltage dependent K+ channel superfamily and includes …
Continue readingIon Channels in Endocrine Pancreatic Cells and their Role in Diabetes
Maintaining glucose homeostasis is an important factor in mammalian physiology, and is controlled to a large extent by the pancreas. …
Continue readingFluorescently-Labeled Toxins: Novel Tools for Working with Live Cells
Venom proteins and peptides have emerged as invaluable tools for research, drug discovery and drug development due to their small …
Continue readingDecoding the L-Type Ca2+ Signal: A Story of Transcription Regulation
L-type voltage-sensitive Ca2+ channels (CaV) on the plasma membrane of diverse cell types play a fundamental role in Ca2+ signaling …
Continue readingGuide to Venom Toxins as Ion Channel Modulators
Venomous creatures deploy a wide array of proteins and peptides, active on a spectrum of targets, for prey immobilization. These …
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