Overview
Alternative Name Naringetol®, Pelargidanon®, Salipurpol®, Salipurol®, Asahina®, Naringenine, (S)-Naringenin, YSO1
Lyophilized Powder yes
Source Synthetic
MW: 272.25
Purity: >98%.
Effective concentration 100 µM - 1mM.
Structure
Chemical name (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4′,5,7-Trihydroxyflavanone.
Molecular formula C15H12O5.
CAS No.: 67604-48-2
Activity Vascular L-type blocker with IC50 = 100 µM1.
References-Activity
- Saponara, S. et al. (2011) Br. J. Pharmacol. 164, 1684.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs (±)-Naringenin inhibits L-type CaV currents expressed in Xenopus oocytes.A. Time course of CaV1.2/α2-δ1/β1 current inhibition by 1 mM (±)-Naringenin (#N-110). Currents were elicited by application of voltage ramps from a holding potential of -100 mV to +50 mV (100 msec). B. Superimposed example traces of current responses before and during perfusion of 1 mM (±)-Naringenin as indicated.
Target L-type Ca2+ channels
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
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