Overview
Alomone Labs is pleased to offer the 5-HT3 Receptor Agonists Explorer Kit (#EK-209). The Explorer Kit contains 5-HT3 receptor agonists, ideal for screening purposes.
Compounds
| Product Name | Cat # | Size |
|---|---|---|
1-Phenylbiguanide hydrochloride |
P-190 | 1 x 1 g |
2-Methyl-5-hydroxytryptamine hydrochloride |
M-170 | 1 x 5 mg |
5-Chloroindole |
C-260 | 1 x 1 g |
5-Hydroxyindole |
H-115 | 1 x 250 mg |
m-Chlorophenylbiguanide hydrochloride |
M-160 | 1 x 500 mg |
RS 56812 hydrochloride |
R-130 | 1 x 5 mg |
Serotonin hydrochloride |
S-165 | 1 x 100 mg |
SR 57227A |
S-155 | 1 x 5 mg |
Scientific Background
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter synthesized from the amino acid tryptophan by the enzyme tryptophan-decarboxylase. This conversion occurs in chromaffin and enteric cells whereas Serotonin reaches the central nervous system via blood circulation. In addition to its function as a neurotransmitter in the CNS it serves as a precursor for melatonin in the pineal gland. It can also be found in non-neuronal tissues such as the mucosa of gut and blood platelets. Serotonin is known to affect numerous behavioral and physiological functions1.
Involved in Serotonin signaling are metabotropic serotonin receptors, ionotropic receptors as well as transporters important for modulating serotonin levels in serotonergic neurons.
- Pithadia, A.B. and Jain, S.M. (2009) J. Clin. Med. Res. 1, 72.
