Cat #: EK-415_KIT
Size: 8 Vials
1-Phenylbiguanide hydrochloride Cat #: P-190
Size:
1 g
Source: Synthetic
MW: 213.67
Purity: >99%
Effective concentration
0.1-100 µM.
Activity
1-Phenylbiguanide hydrochloride is an activator of 5-HT3 channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
25 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
2-Methyl-5-hydroxytryptamine hydrochloride Cat #: M-170
Size:
5 mg
Source: Synthetic
MW: 226.7
Purity: >97%
Effective concentration
0.5-50 µM.
Activity
Methyl serotonin is a 5-HT3 agonist (Ki = 1200 nM) and potent 5-HT6 ligand (Ki = 46 nM)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
5-Chloroindole Cat #: C-260
Size:
1 g
Source: Synthetic
MW: 151.6
Purity: >98%
Effective concentration
1-100 µM.
Activity
5-Chloroindole is a potent and selective allosteric modulator of the 5-HT3 receptor that displays micromolar potency1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
200 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
5-Hydroxyindole Cat #: H-115
Size:
250 mg
Source: Synthetic
MW: 133.15
Purity: >97%
Effective concentration
100 µM – 1 mM.
Activity
5-Hydroxyindole is a 5-HT3 receptor allosteric modulator which slows the desensitization of the channel1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
m-Chlorophenylbiguanide hydrochloride Cat #: M-160
Size:
500 mg
Source: Synthetic
MW: 248.11
Purity: >99%
Effective concentration
0.1-20 µM.
Activity
m-Chlorophenylbiguanide is an activator/agonist of 5-HT3 channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
RS 56812 hydrochloride Cat #: R-130
Size:
5 mg
Source: Synthetic
MW: 347.14
Purity: >96%
Effective concentration
1 nM – 1 µM.
Activity
RS 56812 is a highly potent and selective 5-HT3 partial agonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in water. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Serotonin hydrochloride Cat #: S-165
Size:
100 mg
Source: Synthetic
MW: 212.7
Purity: >98%
Effective concentration
50 nM - 50 µM.
Activity
Serotonin is an endogenous agonist at 5-HT receptors and endogenous substrate for 5-HT transporters. Neurotransmitter that has roles in regulation of mood, emesis, sexuality, sleep and appetite in vivo1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
150 mM in water. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
SR 57227A Cat #: S-155
Size:
5 mg
Source: Synthetic
MW: 248.15
Purity: >96%
Effective concentration
100 nM - 100 µM.
Activity
SR 57227A is a high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50 mM in water. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
