Overview
Cat #: EK-208_KIT
Size: 15 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the 5-HT3 Receptor Antagonist Explorer Kit (#EK-208). The Explorer Kit contains 5-HT3 receptor antagonists, ideal for screening purposes.
For research purposes only, not for human use
Compounds
Product Name | Cat # | Size |
---|---|---|
3-AQC |
A-205_5 mg | 1 x 5 mg |
Azasetron |
A-240_5 mg | 1 x 5 mg |
Azasetron hydrochloride |
Y-100 | 1 x 5 mg |
Bilobalide |
B-145 | 1 x 10 mg |
Ginkgolide B |
G-170 | 1 x 10 mg |
Lerisetron |
L-175 | 1 x 5 mg |
MCI-225 |
M-190 | 1 x 5 mg |
MDL 72222 |
M-155 | 1 x 10 mg |
PU02 |
P-165 | 1 x 5 mg |
SDZ 205-557 hydrochloride |
S-145 | 1 x 5 mg |
Talipexole dihydrochloride |
B-140 | 1 x 5 mg |
Tropanyl-3,5-dimethylbenzoate |
T-135 | 1 x 25 mg |
Tropisetron hydrochloride |
T-125 | 1 x 10 mg |
VUF 10166 |
V-115 | 1 x 5 mg |
Zacopride hydrochloride |
Z-110 | 1 x 5 mg |
Scientific Background
Scientific Background
The 5-HT3 receptor subtype is a member of the Cys-loop ligand-gated cation channels which are expressed throughout the central and peripheral nervous systems and mediates a variety of physiological functions.
5-HT3 receptor antagonists have been established in a number of clinical trials as effective agents in the management and prevention of nausea and vomiting caused by cancer chemotherapy as well as postoperative nausea and emesis after anesthesia and surgery.