Overview
AMPA receptors are members of the glutamate receptor family of ion channels that also include the NMDA and Kainate receptors. The three subfamilies are named after the original synthetic agonists that were identified as selective ligands of each family.
The α-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (AMPA) receptor subfamily includes four members AMPA1-AMPA4 that are also known as GluR1-GluR4 respectively.
The functional AMPA channel is believed to be a tetramer, with most neuronal AMPA receptors being actually heterotetramers composed of AMPA1 plus AMPA2 or AMPA2 plus AMPA3, although homotetramers can also be found.
Alomone Labs is pleased to offer the AMPA Receptor Antagonist Explorer Kit (#EK-210). The Explorer Kit contains AMPA antagonists, ideal for screening purposes.
Compounds
| Product Name | Cat # | Size |
|---|---|---|
CNQX |
C-140 | 1 x 5 mg |
CNQX disodium salt |
C-141 | 1 x 1 mg |
CP 465022 hydrochloride |
C-335 | 1 x 5 mg |
DNQX |
D-131 | 1 x 10 mg |
DNQX disodium salt |
D-130 | 1 x 10 mg |
Evans Blue tetrasodium salt |
E-110 | 1 x 1 g |
GYKI 52466 hydrochloride |
G-125 | 1 x 5 mg |
Kynurenic acid |
K-110 | 1 x 1 g |
Naspm trihydrochloride |
N-215 | 1 x 5 mg |
NBQX |
N-185 | 1 x 5 mg |
NBQX disodium salt |
N-186 | 1 x 1 mg |
PD-160725 2-hydroxyethanesulfonate |
P-280 | 1 x 5 mg |
PhTx-74 |
P-120 | 1 x 1 mg |
Talampanel |
T-185 | 1 x 5 mg |
YM 90K hydrochloride |
Y-105 | 1 x 5 mg |
