Overview
Applications: WB
Reactivity: M, R
Alternative Name Potassium channel subfamily K member 15, Acid-sensitive K+ channel protein TASK-5, TWIK-related acid-sensitive K+ channel 5, K2P15.1
Accession (Uniprot) Number Q8R5I0
Gene ID 156873
For research purposes only, not for human use
Specifications
Applications
Applications
Western blot
- Rat and mouse brain lysates (1:200-1:1000).
Western blot analysis of mouse brain lysates (lanes 1 and 3) and rat brain lysates (lanes 2 and 4):1,2. Anti-KCNK15 (TASK-5) (extracellular) Antibody (#APC-158), (1:200).
3,4. Anti-KCNK15 (TASK-5) (extracellular) Antibody, preincubated with KCNK15/TASK-5 (extracellular) Blocking Peptide (#BLP-PC158).
Scientific Background
Scientific Background
Scientific background
TASK1-5 are members of the two-pore domain K+ channels. They have four transmembrane domains and assist in setting the resting membrane potential.
TASK5 (K2P15.1, KCNK15) was identified using the TASK-3 sequence in a GenBank search. However, when expressed in COS-7 cells, it does not form a functional K+ current1.
The channel is distributed in the brain, heart, lung, kidney, liver, pancreas, adrenal gland and placenta2.
Last Update: 25/03/2025
