Overview
Alternative Name Etodolic acid, Lodine, Ultradol, Lodine XL
Lyophilized Powder yes
Source Synthetic
MW: 287.3
Purity: >98%.
Form Lyophilized powder.
Effective concentration 1-100 µM.
Structure
Chemical name 2-(1,8-diethyl-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl)acetic acid.
Molecular formula C17H21NO3.
CAS No.: 41340-25-4
PubChem CID 3308
Activity Etodolac activates TRPA1 channels with an EC50 value of 10 µM1.
References-Activity
- Inoue, N. et al. (2012) Pharmacology 90, 47.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility Up 200 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Etodolac activates TRPA1 channels expressed in HEK-293 cells.Dose-response curve for the activation of human TRPA1 expressing HEK-293 cells loaded with Calcium 5 dye for changes in intracellular Ca2+ measurements. Calcium signal was apparent with 50 and 100 µM Etodolac (#E-140).
Target TRPA1 channel
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
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