Overview
Lyophilized Powder yes
Source Synthetic
MW: 244.28
Purity: >98%.
Effective concentration 1-100 µM.
Structure
Chemical name Ethyl 3-(1-phenylethyl)imidazole-4-carboxylate.
Molecular formula C14H16N2O2.
CAS No.: 33125-97-2
PubChem CID 36339
Activity Etomidate greatly potentiated GABA responses of α1/β2/γ2 channels in oocytes (3.2 μM)1. It is also a potent and selective 5-HT3A and 3B receptor antagonist2.
References-Activity
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility 35 mg/ml in ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Etomidate blocks 5-HT3A receptors expressed in HEK 293T cells.Currents were elicited by 10 µM 5-HT, delivered every 3 minutes. Etomidate (#E-200) was applied 30 seconds before stimulation at 100 and 200 µM, as indicated and inhibited the 5-HT induced current in a dose-dependent and reversible manner.
Target 5-HT3A/B channels
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
