Overview
Alternative Name Ifenprodil tartrate, Ifenprodil hemitartrate
Lyophilized Powder yes
Source Synthetic
MW: 801
Purity: >98%.
Form Lyophilized powder.
Effective concentration 0.1-100 µM.
Structure
Chemical name 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol;2,3-dihydroxybutanedioic acid OR α-(4-Hydroxyphenyl)-β-methyl-4-benzyl-1-piperidineethanol (+)-tartrate salt.
Molecular formula C46H60N2O10.
CAS No.: 23210-58-4
PubChem CID 11957579
Activity Ifenprodil inhibits NMDA receptors with the following IC50s: 0.15 μM (NR2B), 39 μM (NR2A), 29 μM (NR2C)1.
References-Activity
- Traynelis, S.F. et al. (2010) Pharmacol. Rev. 62, 405.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility Up to 10 mM in water or ethanol. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Ifenprodil (+)-tartrate salt (hemitartrate salt) inhibits NMDA (NR1+NR2A) channels expressed in Xenopus oocytes.A. Time course of NMDA currents elicited with 100 µM glutamate and 100 µM Glycine, every 50s, while membrane potential was held at -80 mV. 100 µM Ifenprodil (+)-tartrate salt (hemitartrate salt) (#I-105), applied for 3 min, as indicated, reversibly inhibited current amplitude. B. superimposed current traces taken from the experiment described in A.
Target NMDA receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
