Cat #: EK-122_KIT
Size: 9 Vials
Form: Lyophilized
Apamin Cat #: STA-200
Size:
0.5 mg
MW: 2028 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
100 nM - 1 µM.
Activity
Apamin is a blocker of voltage-independent Ca2+-activated K+ (SK) channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or two months at -20°C.
CyPPA Cat #: C-110
Size:
5 mg
Source: Synthetic
MW: 285.4
Purity: >98%
Effective concentration
1-100 μM.
Activity
CyPPA is an activator of small conductance Ca2+-activated K+ channels KCa2.2 (SK2) and KCa2.3 (SK3) with EC50 values of 5.6 and 14 μM for SK3 and SK2 respectively. It displays no activity at SK1 and intermediate conductance KCa (IK) channels1. CyPPA blocks TRPM7 channels2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO or ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
1-EBIO Cat #: E-150
Size:
10 mg
Source: Synthetic
MW: 162.19
Purity: >97%
Effective concentration
5-100 μM.
Activity
1-EBIO is an activator of KCa3.1 and KCa2 channel currents1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
250 mM DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
NS-309 Cat #: N-180
Size:
5 mg
Source: Synthetic
MW: 231.04
Purity: >99% (HPLC)
Effective concentration
0.1 - 10 µM.
Activity
NS-309 is a positive modulator of small- and intermediate- conductance Ca2+-activated K+ (KCa2 and KCa3.1) channels, with EC50 values of 30 and 10 nM, respectively1. NS-309 also blocks L-type Ca2+ channels with IC50 value of 10 μM2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
NS-4591 Cat #: N-325
Size:
5 mg
Source: Synthetic
MW: 258.03
Purity: >98% (HPLC)
Effective concentration
0.01-5 μM.
Activity
NS-4591 is a potent SK4 channel activator; 30 nM doubled KCa3.1 currents in HEK cells1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
NS8593 hydrochloride Cat #: N-195
Size:
5 mg
Source: Synthetic
MW: 299.79
Purity: >99%
Effective concentration
100 nM -10 µM.
Activity
NS8593 is KCa2 (SK) channel blocker, with no activity towards KCa3.1 channels, with IC50~100 nM1,2. It also blocks TRPM7 channels3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50 mM DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Scyllatoxin Cat #: STS-370
Size:
0.1 mg
MW: 3423 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
20-200 nM.
Activity
Scyllatoxin inhibits small conductance Ca2+-activated K+ channels (SK)1-3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
SKA-31 Cat #: S-120
Size:
5 mg
Source: Synthetic
MW: 200.2
Purity: >98%
Effective concentration
0.1-10 µM.
Activity
SKA-31 is an activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively)1. Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice1,2. SKA-31 blocks TRPM73.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Tamapin Cat #: STT-400
Size:
0.1 mg
MW: 3458.16 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
500 pM - 50 nM.
Activity
Tamapin blocks KCa2 channels. Tamapin displays a remarkable selectivity for KCa2.2 versus KCa2.1 channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
