Cat #: EK-103_KIT
Size: 7 Vials
Form: Lyophilized
Benidipine hydrochloride Cat #: B-120
Size:
5 mg
Source: Synthetic
MW: 542
Purity: >99% (HPLC)
Effective concentration
1-100 µM.
Activity
Benidipine hydrochloride is a state-dependent Ca2+ channel blocker. It inhibits N-type and P/Q-type channels with IC50 of ~30 µM and is an order of magnitude more potent towards L-type channels, exhibiting the following IC50: 14 µM at -80mV and 5 µM at -60 mV holding potentials1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Calcicludine Cat #: SPC-650
Size:
70 µg
MW: 6979 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
500 nM.
Activity
Calcicludine is a potent and specific antagonist of neuronal L-type CaV channels1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
Calciseptine Cat #: SPC-500
Size:
70 µg
MW: 7036 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
500 nM.
Activity
Calciseptine is a specific antagonist of L-type CaV channels1.
Storage before reconstitution
Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
FS-2 Cat #: F-700
Size:
70 µg
MW: 7026 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Natural peptide isolated from Dendroaspis polylepis polylepis (Black mamba snake).
Effective concentration
100 nM - 2 ֲµM.
Activity
FS-2 is an L-type CaV channel blocker1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
L-651,582 Cat #: L-110
Size:
5 mg
Source: Synthetic
MW: 424.7
Purity: >99%
Effective concentration
0.5-200 μM.
Activity
L-651,582 inhibits CaV channels as well as receptor activated Ca2+ signals in guinea pig atrial cells1, thus it is an L-type, voltage-gated Ca2+ channel blocker with additional antiproliferative activities2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Lomerizine dihydrochloride Cat #: L-125
Size:
50 mg
Source: Synthetic
MW: 541.5
Purity: >99%
Effective concentration
0.5-100 µM.
Activity
Lomerizine dihydrochloride inhibited CaV currents in PC12 cells with IC50 of 1.9 µM1. It inhibits L-type Ca2+ channels2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
SR 33805 oxalate Cat #: S-105
Size:
5 mg
Source: Synthetic
MW: 654.77
Purity: >96%
Effective concentration
1 nM - 10 μM.
Activity
SR 33805, a fantofarone derivative, is a potent Ca2+ channel antagonist1. It binds allosterically to the α1-subunit of L-type Ca2+ channels (Kd = 20 pM), at a site distinct from other types of blockers2. It potently inhibits the Ca2+ channel in primary mouse cardiac myocytes cultures with IC50 values ranging from 4 to 33 nM3.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
