Overview
Alternative Name Cardiovasc®, Corifeo®, Carmen®, Lerzam®, Lercanidipine HCl, Rec-15/2375, Lercadip®, Lercapin®
Lyophilized Powder yes
Source Synthetic
MW: 648.2
Purity: >98%.
Effective concentration 1-100 µM.
Structure
Chemical name 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride.
Molecular formula C36H42ClN3O6.
CAS No.: 132866-11-6
Activity 10 µM were effective in abolishing Ang II mediated smooth muscle contraction1.
References-Activity
- Arun, K.H. et al. (2005) Cardiovasc. Res. 65, 374.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Lercanidipine hydrochloride inhibits L-type voltage-gated Ca2+ currents expressed in Xenopus oocytes.A. Time course of CaV1.2/α2-δ1/β2a current inhibition by 10 and 30 µM Lercanidipine hydrochloride (#L-115). Currents were elicited by application of voltage steps from a holding potential of -80 mV to 0 mV (100 msec). B. Superimposed example traces of current responses before and during perfusion of 10 and 30 µM Lercanidipine hydrochloride (as indicated).
Target L-type Ca2+ channels
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
