Overview
Cat #: AK-305_KIT
Size: 18 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the Mechanosensitive TRP Channel Antibody Explorer Kit (#AK-305). This Explorer Kit includes mechanosensitive TRP channel antibodies with their respective peptide control antigen. An ideal tool for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
Anti-TRPA1 (extracellular) Antibody |
ACC-037 | 1 x 50 µl |
TRPA1 (extracellular) Blocking Peptide |
BLP-CC037 | 1 x 40 µg |
Anti-TRPC1 Antibody |
ACC-010 | 1 x 50 µl |
TRPC1 Blocking Peptide |
BLP-CC010 | 1 x 40 µg |
Anti-TRPC1 (extracellular) Antibody |
ACC-118 | 1 x 50 µl |
TRPC1 (extracellular) Blocking Peptide |
BLP-CC118 | 1 x 40 µg |
Anti-TRPC6 Antibody |
ACC-017 | 1 x 50 µl |
TRPC6 Blocking Peptide |
BLP-CC017 | 1 x 40 µg |
Guinea pig Anti-TRPC6 Antibody |
ACC-017-GP (formerly AGP-002) | 1 x 50 µl |
TRPC6 Blocking Peptide |
BLP-CC017 | 1 x 40 µg |
Anti-TRPC6 (extracellular) Antibody |
ACC-120 | 1 x 50 µl |
TRPC6 (extracellular) Blocking Peptide |
BLP-CC120 | 1 x 40 µg |
Anti-TRPP1 (PKD2) Antibody |
ACC-052 | 1 x 50 µl |
TRPP1/PKD2 Blocking Peptide |
BLP-CC052 | 1 x 40 µg |
Anti-TRPV4 Antibody |
ACC-034 | 1 x 50 µl |
TRPV4 Blocking Peptide |
BLP-CC034 | 1 x 40 µg |
Anti-TRPV4 (extracellular) Antibody |
ACC-124 | 1 x 50 µl |
TRPV4 (extracellular) Blocking Peptide |
BLP-CC124 | 1 x 40 µg |
Scientific Background
Scientific Background Mechanosensitive ion channels (MS channels) represent a diverse population of ion channels. Other membrane-associated proteins with different biophysical properties apart from ion channels, specialized cytoskeletal proteins, cell junction molecules and G-protein-coupled receptors and kinases, among many others are also considered mechanosensitive. MS channels integrate a variety of mechanical stimuli such as shear stress, tension, torsion, and compression and translate them into short-term effects (i.e. changes in ion concentrations and voltage) and long-term effects via changes in gene expression.
