Overview
Alternative Name Zispin, Remergil, Remeron, 6-Azamianserin, Remergon
Lyophilized Powder yes
Source Synthetic
MW: 265.4
Purity: >99.5%.
Effective concentration 10 nM – 1 µM.
Structure
Chemical name 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine.
Molecular formula C17H19N3.
CAS No.: 61337-67-5
PubChem CID 4205
Activity Mirtazipine is an antidepressant agent; potent 5-HT2, 5-HT3 and histamine H1 receptor antagonist and moderately potent α2-adrenoceptor antagonist1.
References-Activity
- Kooyman, A.R. et al. (1994) Neuropharmacology. 33, 501.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility 25-50 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Mirtazapine blocks 5-HT3A receptors expressed in HEK 293T cells.5-HT3A receptor currents were elicited with 10 µM 5-HT, delivered every 3 minutes. Mirtazapine (#M-130) was applied 30 seconds before stimulation at 10 nM, 100 nM and 1 µM as indicated and inhibited the 5-HT induced current in a dose-dependent and reversible manner.
Target 5-HT3, 5-HT2, Histamine H1, α2 adrenergic receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
