Overview
Alternative Name Gasmotin citrate, TAK-370 citrate, AS-4370 citrate
Lyophilized Powder yes
Source Synthetic
MW: 614
Purity: >99%.
Effective concentration 5-500 µM.
Structure
Chemical name 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid.
Molecular formula C27H33ClFN3O10.
CAS No.: 112885-42-4
PubChem CID 119583
Activity Mosapride citrate is a 5-HT4 receptor agonist and 5-HT3 receptor antagonist1.
References-Activity
- Mine, Y. et al. (1997) J. Pharmacol. Exp. Ther. 283, 1000.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility 100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Mosapride citrate blocks 5-HT3A receptors expressed in HEK 293T cells.5-HT3A receptor currents were elicited with 10 µM 5-HT, delivered every 3 minutes. Mosapride citrate (#M-225) was applied 30 seconds before stimulation at 50, 100 and 330 µM as indicated and inhibited the 5-HT induced current in a dose dependent and reversible manner.
Target 5-HT3 and 5-HT4 receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
