Cat #: AK-365_KIT
Size: 28 Vials
Form: Lyophilized
Application key:
CBE- Cell-based ELISA, FC- Flow cytometry, ICC- Immunocytochemistry, IE- Indirect ELISA, IF- Immunofluorescence, IFC- Indirect flow cytometry, IHC- Immunohistochemistry, IP- Immunoprecipitation, LCI- Live cell imaging, N- Neutralization, WB- Western blot
Species reactivity key:
H- Human, M- Mouse, R- Rat
Anti-SCN1A (NaV1.1) Antibody Cat #: ASC-001
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, IP, WB
Reactivity:
H, M, R
Immunogen
Peptide (C)TASEHSREPSAAGRLSD, corresponding to amino acid residues 465-481 of rat NaV1.1 (Accession P04774). Intracellular loop between domains I and II.
Homology
Mouse, human - identical.
SCN1A/Nav1.1 Blocking Peptide Cat #: BLP-SC001
Size:
40 µg
Guinea pig Anti-SCN1A (NaV1.1) Antibody Cat #: ASC-001-GP
Size:
50 µl
Host: Guinea pig
Type: Polyclonal
Application:
WB
Reactivity:
H, M, R
Immunogen
Peptide (C)TASEHSREPSAAGRLSD, corresponding to amino acid residues 465-481 of rat NaV1.1 (Accession P04774). Intracellular loop between domains I and II.
Homology
Mouse, human - identical.
SCN1A/Nav1.1 Blocking Peptide Cat #: BLP-SC001
Size:
40 µg
Anti-SCN3A (NaV1.3) Antibody Cat #: ASC-004
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, IP, WB
Reactivity:
H, M, R
Immunogen
Peptide (C)HLEGNHRADGDRFP, corresponding to amino acid residues 511-524 rat NaV1.3 (Accession P08104). Intracellular, loop between domains I and II.
Homology
Mouse - 12/14 amino acid residues identical.
SCN3A/Nav1.3 Blocking Peptide Cat #: BLP-SC004
Size:
40 µg
Anti-SCN3A (NaV1.3) (extracellular) Antibody Cat #: ASC-023
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, LCI, WB
Reactivity:
R
Immunogen
Peptide CSQWPPSDSAFE, corresponding to amino acid residues 277-288 of rat NaV1.3 (Accession P08104). 3rd extracellular loop, domain I.
Homology
Mouse, human – 11/12 amino acid residues identical.
SCN3A/Nav1.3 (extracellular) Blocking Peptide Cat #: BLP-SC023
Size:
40 µg
Anti-NaV1.6 (SCN8A) Antibody Cat #: ASC-009
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, WB
Reactivity:
H, M, R
Immunogen
Peptide CIANHTGVDIHRNGDFQKNG, corresponding to amino acid residues 1042-1061 of rat NaV1.6 (Accession O88420). Intracellular loop between domains II and III.
Homology
Mouse - identical; human - 19/20 amino acid residues identical.
Nav1.6/SCN8A Blocking Peptide Cat #: BLP-SC009
Size:
40 µg
Anti-NaV1.7 (SCN9A) Antibody Cat #: ASC-008
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, WB
Reactivity:
H, M, R
Immunogen
Peptide (C)EFTSIGRSR IMGLSE, corresponding to amino acid residues 446-460 of rat NaV1.7 (Accession O08562). Intracellular loop between domains I and II.
Homology
Rabbit - 14/15 amino acid residues identical; human, mouse - 13/15 amino acid residues identical.
Nav1.7/SCN9A Blocking Peptide Cat #: BLP-SC008
Size:
40 µg
Anti-NaV1.7 (SCN9A) (extracellular) Antibody Cat #: ASC-027
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, LCI, WB
Reactivity:
R
Immunogen
Peptide (C)EKEGQTEYMDY(K), corresponding to amino acid residues 1533-1543 of rat NaV1.7 (Accession O08562). 1st extracellular loop, domain IV.
Homology
Mouse - 8/11 amino acid residues identical.
Human - Not recommended to use with human samples.
Human - Not recommended to use with human samples.
Nav1.7/SCN9A (extracellular) Blocking Peptide Cat #: BLP-SC027
Size:
40 µg
Guinea pig Anti-NaV1.7 (SCN9A) Antibody Cat #: ASC-008-GP
Size:
50 µl
Host: Guinea pig
Type: Polyclonal
Application:
WB
Reactivity:
R
Immunogen
Peptide (C)EFTSIGRSR IMGLSE, corresponding to amino acid residues 446-460 of rat NaV1.7 (Accession O08562). Intracellular loop between domains I and II.
Homology
Human, mouse - 13/15 amino acid residues identical.
Nav1.7/SCN9A Blocking Peptide Cat #: BLP-SC008
Size:
40 µg
Anti-NaV1.8 (SCN10A) Antibody Cat #: ASC-016
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, IP, WB
Reactivity:
M, R
Immunogen
Peptide (C)EDEVAAKEGNSPGPQ, corresponding to amino acid residues 1943-1956 of rat NaV1.8 (Accession Q63554). Intracellular, C-terminus.
Homology
Mouse - 14/15 amino acid residues identical; human - 7/15 amino acid residues identical.
Nav1.8/SCN10A Blocking Peptide Cat #: BLP-SC016
Size:
40 µg
Anti-NaV1.8 (SCN10A) (extracellular) Antibody Cat #: ASC-028
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
WB
Reactivity:
M, R
Immunogen
Peptide (C)EDNYLEEKPRVKSVLE, corresponding to amino acid residues 1173-1188 of rat NaV1.8 (Accession Q62968). 1st extracellular loop, domain III.
Homology
Mouse - identical; human – Not recommended for use with human samples.
Nav1.8/SCN10A (extracellular) Blocking Peptide Cat #: BLP-SC028
Size:
40 µg
Guinea pig Anti-NaV1.8 (SCN10A) Antibody Cat #: ASC-016-GP
Size:
50 µl
Host: Guinea pig
Type: Polyclonal
Application:
IF, IH, WB
Reactivity:
R
Immunogen
Peptide (C)EDEVAAKEGNSPGPQ, corresponding to amino acid residues 1943-1956 of rat NaV1.8 (Accession Q63554). Intracellular, C-terminus.
Homology
Mouse - 14/15 amino acid residues identical; human - 7/15 amino acid residues identical.
Nav1.8/SCN10A Blocking Peptide Cat #: BLP-SC016
Size:
40 µg
Anti-SCN11A (NaV1.9) Antibody Cat #: ASC-017
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IC, IF, IH, WB
Reactivity:
H, M, R
Immunogen
Peptide CNGDLSSLDVAKVKVHND, corresponding to amino acid residues 1748-1765 of rat NaV1.9 (Accession O88457). Intracellular, C-terminus.
Homology
Mouse - 15/18 amino acid residues identical; human - 14/18 amino acid residues identical.
SCN11A/Nav1.9 Blocking Peptide Cat #: BLP-SC017
Size:
40 µg
Guinea pig Anti-SCN11A (NaV1.9) Antibody Cat #: ASC-017-GP
Size:
50 µl
Host: Guinea pig
Type: Polyclonal
Application:
IF, IH, WB
Reactivity:
R
Immunogen
Peptide CNGDLSSLDVAKVKVHND, corresponding to amino acid residues 1748-1765 of rat NaV1.9 (Accession O88457). Intracellular, C-terminus.
Homology
Mouse - 15/18 amino acid residues identical; human - 14/18 amino acid residues identical.
SCN11A/Nav1.9 Blocking Peptide Cat #: BLP-SC017
Size:
40 µg
Anti-SCN2B (NaVβ2) Antibody Cat #: ASC-007
Size:
50 µl
Host: Rabbit
Type: Polyclonal
Application:
IF, IH, WB
Reactivity:
H, M, R
Immunogen
Peptide (C)KTEEEGKTDGEGNAEDGAK, corresponding to amino acid residues 197-215 of rat β2 subunit of voltage-gated Na+ channels (Accession P54900). Intracellular, C-terminus.
Homology
Human - 17/19 amino acid residues identical.
SCN2B/Navβ2 Blocking Peptide Cat #: BLP-SC007
Size:
40 µg
Antibody Storage & Reconstitution Instructions
Storage before reconstitution
Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Add deionized water, depending on the sample size.
Storage after reconstitution
The reconstituted solution can be stored at 4°C for up to 2 weeks. For longer periods, small aliquots should be stored at -20°C or below.
Avoid multiple freezing and thawing. The further dilutions should be made using a carrier protein such as BSA (1%). Centrifuge all antibody preparations before use (10000 × g 5 min).
Control antigen storage before reconstitution
Lyophilized powder can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Control antigen reconstitution
100 μl water.
Control antigen storage after reconstitution
-20ºC.
Preadsorption control
1 μg peptide per 1 μg antibody.
Note
Guinea pig polyclonal antibodies (#ASC-001-GP, #ASC-008-GP, #ASC-016-GP, & #ASC-017-GP) are included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
For research purposes only, not for human use
