Overview
Lyophilized Powder yes
Source Synthetic
MW: 360.4
Purity: >98%.
Effective concentration 1-200 µM.
Structure
Chemical name Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(meta-nitrophenyl)-3,5-pyridinedicarboxylate.
Molecular formula C18H20N2O6.
CAS No.: 39562-70-4
Activity 10 μM inhibited 50% of L-type current expressed in Xenopus oocytes, with no effect on T-type channels.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Nitrendipine inhibits L-type voltage-gated Ca2+ currents expressed in Xenopus oocytes.A. Time course of CaV1.2/α2-δ1/β2a (L-type) current inhibition by 200 µM of Nitrendipine (#N-155). Currents were elicited by application of voltage steps from a holding potential of -100 mV to 0 mV (100 msec). B. Superimposed example traces of current responses before and during perfusion of 200 µM Nitrendipine as indicated.
Target L-type Ca2+ channels
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
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