Cat #: EK-350_KIT
Size: 11 Vials
Form: Lyophilized
7-Chlorokynurenic acid sodium salt Cat #: C-286
Size:
5 mg
Source: Synthetic
MW: 245.59
Purity: >98%
Effective concentration
1-100 µM.
Activity
7-Chlorokynurenic acid is an NMDA receptor antagonist that acts at the glycine site with IC50 of 3.4 μM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50 mM in H2O. Centrifuge all product preparations before use (10,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
α-Asarone Cat #: A-260
Size:
1 g
Source: Natural
MW: 208.3
Purity: >99%
Origin
Acorus tatarinowii.
Effective concentration
1-500 µM.
Activity
α-Asarone 100 μM to 1 mM inhibits NaV1.2 channel currents. It also blocks GABA(A) receptors in neurons1. α-Asarone blocks corticosterone-induced anxiety-like behaviours via modulating TrkB signaling process2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Arcaine sulfate Cat #: A-285
Size:
25 mg
Source: Synthetic
MW: 270.31
Purity: >95%
Effective concentration
50-500 µM.
Activity
Arcane is an NMDA receptor antagonist with KD of 61 µM at -60 mV1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
20 mM in water. Centrifuge all product preparations before use (10,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
CGS 19755 Cat #: C-310
Size:
5 mg
Source: Synthetic
MW: 223.16
Purity: >95%
Effective concentration
0.01-10 µM.
Activity
CGS 19755 is a potent and competitive NMDA receptor antagonist1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
20 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
CNS-1102 Cat #: C-305
Size:
5 mg
Source: Synthetic
MW: 339.86
Purity: >99%
Effective concentration
1 nM – 1 µM.
Activity
CNS-1102 is a potent, use-dependent, non-competitive blocker of NMDA receptors, exhibiting high affinity for the central ion channel site (IC50 = 36 nM versus [3H]-MK-801)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 100 mM in DMSO and to 50 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
(±)-CPP Cat #: C-175
Size:
5 mg
Source: Synthetic
MW: 252.2
Purity: >93%
Effective concentration
10 nM - 10 µM.
Activity
(±)-CPP is a competitive NMDA receptor antagonist. IC50= 0.04 μM (NR2A), 0.3 μM (NR2B), 0.3 μM (NR2C)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
100 mM in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
D-AP5 Cat #: D-145
Size:
1 mg
Source: Synthetic
MW: 197.1
Purity: >95%
Effective concentration
100 nM - 100 µM.
Activity
D-AP5 is an NMDA receptor antagonist. IC50 = 0.28 µM (NR2A), 0.46 µM (NR2B), 1.6 µM (NR2C)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
25 mg/ml in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
DL-AP5 Cat #: D-140
Size:
5 mg
Source: Synthetic
MW: 197.1
Purity: >95%
Effective concentration
100 nM - 100 µM.
Activity
DL-AP5 is an NMDA receptor antagonist. IC50 = 0.28 µM (NR2A), 0.46 µM (NR2B), 1.6 µM (NR2C)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
50 mg/ml in NaOH (1 M), 5 mg/ml in H2O. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Eliprodil Cat #: E-155
Size:
5 mg
Source: Synthetic
MW: 347.9
Purity: >99%
Effective concentration
0.1-10 µM.
Activity
Eliprodil is a non-competitive NR2B-selective NMDA glutamate receptor antagonist 1, N and P-type voltage-dependent Ca2+ channels blocker 2.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
>25 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Kynurenic acid Cat #: K-110
Size:
1 g
Source: Synthetic
MW: 189.2
Purity: >98%
Effective concentration
1 µM - 2 mM.
Activity
Kynurenic acid antagonizes ionotropic glutamate receptors with IC50 values of 33 µM (GluK2), 130 µM (GluK1). 100 µM - 3mM antagonizes NMDA response in rat spinal cord.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 50mM in DMSO or in equimolar NaOH. Mild warming (37°C-42°C) and agitation may be required.
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
(+)-MK 801 maleate Cat #: M-230
Size:
5 mg
Source: Synthetic
MW: 337.4
Purity: >99% (HPLC)
Effective concentration
0.01-10 µM.
Activity
(+)-MK 801 maleate is a potent, selective and non-competitive NMDA receptor antagonist with an IC50 of 0.01 μM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
