Overview
Alternative Name Olmesartan Acid, Votum
Lyophilized Powder yes
Source Synthetic
MW: 446.5
Purity: ≥99%.
Effective concentration 1 nM – 1 µM.
Structure
Chemical name 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid.
Molecular formula C24H26N6O3.
CAS No.: 144689-24-7
PubChem CID 158781
Activity Olmesartan is an Angiotensin II Type 1 Receptor Antagonist1.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility 20 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Olmesartan inhibits the activation of Angiotensin AT1R expressed in CHO-K1-mt Aequorin-Gα16 cells.Dose response curve for the inhibition of AT1R expressed in CHO-K1-mt Aequorin-Gα16 cells. Ca2+ response, as detected by elevation in aequorin derived fluorescence following 0.04 nM Angiotensin II application, was inhibited by increasing concentrations of Olmesartan (#O-125). 1 µM Olmesartan fully inhibited the activation by Angiotensin II.
Target AT1R angiotensin receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
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