Overview
Cat #: AK-100_KIT
Size: 22 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the P2Y Receptor Antibody Explorer Kit (#AK-100). This Explorer Kit includes antibodies directed to purinergic P2Y receptors.
For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background Hypoxia or inflammation, activates the release of extracellular nucleotides such as ATP and UTP which interact with cell surface P2Y receptors to produce a broad range of physiological responses including cardiac function, platelet aggregation and smooth muscle cell proliferation. Eight mammalian P2Y receptors, members of the G-protein coupled receptor superfamily, have been identified on the basis of sequence homology and pharmacological profile: P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13 and P2Y14.
References
- Abbracchio, M.P. et al. (2006) Pharmacol. Rev. 58, 281.
- Wang, L. et al. (2002) J. Cardiovasc. Pharmacol. 40, 841.
