Overview
Cat #: AK-218_KIT
Size: 13 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the SK (Non-BKCa) Channel Antibody Explorer Kit (#AK-218). The Explorer Kit contains non-BKCa channel antibodies, ideal for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
Anti-KCNN1 (KCa2.1, SK1) Antibody |
APC-039 | 1 x 50 µl |
KCNN1/KCa2.1 Blocking Peptide |
BLP-PC039 | 1 x 40 µg |
Anti-KCNN2 (KCa2.2, SK2) Antibody |
APC-028 | 1 x 50 µl |
KCNN2/KCa2.2 Blocking Peptide |
BLP-PC028 | 1 x 40 µg |
Guinea pig Anti-KCNN2 (KCa2.2, SK2) Antibody |
APC-028-GP (formerly AGP-045) | 1 x 50 µl |
KCNN2/KCa2.2 Blocking Peptide |
BLP-PC028 | 1 x 40 µg |
Anti-KCNN3 (KCa2.3, SK3) (N-term) Antibody |
APC-025 | 1 x 50 µl |
KCNN3/KCa2.3 (N-term) Blocking Peptide |
BLP-PC025 | 1 x 40 µg |
Anti-KCNN3 (KCa2.3, SK3) (C-term) Antibody |
APC-103 | 1 x 50 µl |
KCNN3/KCa2.3 (C-term) Blocking Peptide |
BLP-PC103 | 1 x 40 µg |
Anti-KCNN4 (KCa3.1, SK4) Antibody |
APC-064 | 1 x 50 µl |
KCNN4/KCa3.1 Blocking Peptide |
BLP-PC064 | 1 x 40 µg |
Mouse Anti-KCNN4 (KCa3.1, SK4) (extracellular) Antibody |
ALM-051 | 1 x 25 µg |
Scientific Background
Scientific Background Ca2+-dependent K+ (KCa) channels are divided according to biophysical properties and gene homology into two main groups. KCa were first divided according to their single channel conductance, which represents the speed by which the K+ passes via the open channel. The first group consists of small and intermediate conductance channels (SK and IK respectively, the KCNN gene family). The second group is comprised of large/big conductance channels (called BKCa or maxi K+, encoded by the slo or KCNMA1 gene)1.
References
- Coetzee, W.A. et al. (1999) Annals N.Y. Acad. Sci. 868, 233.
