Overview
Cat #: AK-525_KIT
Size: 16 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the SNARE Complex Antibody Explorer Kit (#AK-525). The Explorer Kit contains SNARE complex antibodies, ideal for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
Anti-Alpha-Synuclein Antibody |
APZ-035 | 1 x 50 µl |
Alpha-Synuclein Blocking Peptide |
BLP-PZ035 | 1 x 40 µg |
Anti-SNAP-25 Antibody |
ANR-001 | 1 x 50 µl |
SNAP-25 Blocking Peptide |
BLP-NR001 | 1 x 50 µg |
Anti-Synaptotagmin-1 (SYT1) Antibody |
ANR-003 | 1 x 50 µl |
Synaptotagmin-1/SYT1 Blocking Peptide |
BLP-NR003 | 1 x 40 µg |
Anti-Syntaxin 1 Antibody |
ANR-002 | 1 x 50 µl |
Syntaxin 1 Blocking Peptide |
BLP-NR002 | 1 x 60 µg |
Anti-Syntaxin 2 Antibody |
ANR-008 | 1 x 50 µl |
Syntaxin 2 Blocking Peptide |
BLP-NR008 | 1 x 20 µg |
Anti-Syntaxin 3 Antibody |
ANR-005 | 1 x 50 µl |
Syntaxin 3 Blocking Peptide |
BLP-NR005 | 1 x 40 µg |
Anti-Syntaxin 4 Antibody |
ANR-004 | 1 x 50 µl |
Syntaxin 4 Blocking Peptide |
BLP-NR004 | 1 x 40 µg |
Anti-VAMP-2 Antibody |
ANR-007 | 1 x 50 µl |
VAMP-2 Blocking Peptide |
BLP-NR007 | 1 x 0.12 mg |
Scientific Background
Scientific Background
SNARE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion1,2.
SNAREs can be roughly divided into vesicular (v-SNAREs) and target (t-SNAREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cognate v-/t-SNAREs between two opposing membranes generates trans-SNARE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion.
References
- Jahn, R. and Scheller, R.H. (2006) Nat. Rev. Mol. Cell Biol. 7, 631.
- Südhof, T.C. and Rothman, J.E. (2009) Science 323, 474.
