Cat #: EK-120_KIT
Size: 11 Vials
Form: Lyophilized
A 967079 Cat #: A-225_5 mg
Size:
5 mg
Source: Synthetic
MW: 207.2
Purity: >99% (HPLC)
Effective concentration
10 nM - 100 µM.
Activity
A 967079 is a blocker of TRPA1 channels and has IC50 values of 67 and 289 nM at human and rat TRPA1 receptors respectively1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 200 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
AP-18 Cat #: A-250
Size:
5 mg
Source: Synthetic
MW: 209.7
Purity: >99% (HPLC)
Effective concentration
1-100 µM.
Activity
AP-18 has an IC50 of 3.1 and 4.5 μM for human and mouse TRPA1, respectively1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 200 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Chembridge-5861528 Cat #: C-235
Size:
5 mg
Source: Synthetic
MW: 369.4
Purity: >99%
Effective concentration
0.1-10 µM.
Activity
Chembridge-5861528 blocks TRPA1 channels and has an IC50 of 0.3 µM in rat-TRPA1 transfected HEK 293 cells1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Curcumin Cat #: C-230
Size:
5 g
Source: Natural
MW: 368.4
Purity: >96%
Origin
Curcuma longa L. root.
Effective concentration
10-200 µM.
Activity
Curcumin activates TRPA1 channels with an EC50 of 10 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
5-(N,N-Dimethyl)amiloride hydrochloride Cat #: D-165
Size:
5 mg
Source: Synthetic
MW: 294.1
Purity: >99% (HPLC)
Effective concentration
1-100 µM.
Activity
5-(N,N-Dimethyl)amiloride hydrochloride blocks TRPA1 channels with an IC50 of 80 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 50 mM in methanol. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
HC-030031 Cat #: H-105
Size:
10 mg
Source: Synthetic
MW: 355.4
Purity: >99%
Effective concentration
1-100 µM.
Activity
HC-030031 has an IC50 of 5 μM for antagonizing formalin-evoked Ca2+ influx1. It blocks TRPA1 channels.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up to 100 mM in DMSO. Centrifuge all product preparations before use (5,000 x g for 1 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
Ligustilide Cat #: L-170
Size:
10 mg
Source: Natural
MW: 190.2
Purity: >95%
Origin
Angelica sinensis.
Effective concentration
10-200 µM.
Activity
Ligustilide activates TRPA1 with an EC50 of 44 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Up 100 mM in DMSO and 50 mM in Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to four weeks at 4°C or three months at -20°C.
4-ONE Cat #: O-145
Size:
5 mg
Source: Synthetic
MW: 154.2
Purity: >97%
Effective concentration
1-100 µM.
Activity
4-ONE (4-Oxo-2-nonenal) is a lipid peroxidation product with multiple biological activities, shown to activate TRPA1 channels (EC50 = 1.9 µM)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -80°C. Store tightly sealed.
Reconstitution
Supplied in oil form. Soluble in DMSO, methanol, ethanol.
Centrifuge all products before use (10000 x g 5 min).
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
-20°C.
Ononetin Cat #: O-135
Size:
50 mg
Source: Synthetic
MW: 258.27
Purity: >98%
Effective concentration
10-100 µM.
Activity
Ononetin is a deoxybenzoin, a potent blocker of TRPM3 channels (IC50 = 0.3 µM), also shown to activate TRPA1 channels at 10-100 µM1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Protect from light.
Reconstitution
Soluble in DMSO and ethanol.
Centrifuge all products before use (10000 x g 5 min).
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
Up to three months at -20°C.
Optovin Cat #: O-140
Size:
5 mg
Source: Synthetic
MW: 315.41
Purity: >98%
Effective concentration
10-100 µM.
Activity
Optovin is a photosensitive TRPA1 ligand that activates TRPA1 channels in vitro and facilitates repeated photoactivation of motor behaviors in vivo (EC50 = 2 µM) when reversibly activated by violet light (405 nm)1.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C. Protect from light.
Reconstitution
Soluble in DMSO.
Centrifuge all products before use (10000 x g 5 min).
Centrifuge all products before use (10000 x g 5 min).
Storage after reconstitution
Up to three months at -20°C.
ProTx-I Cat #: STP-400
Size:
0.1 mg
MW: 3988 Da
Purity: >98% (HPLC)
Net peptide content: 100%
Origin
Synthetic peptide
Effective concentration
10-100 nM.
Activity
ProTx-I inhibits voltage-gated Ca2+ (CaV3.1), K+ (KV2.1), and all Na+ channels tested (NaV1.2, NaV1.5, NaV1.7 and NaV1.8). The toxin shifts the voltage-dependence of channel activation to more positive potentials.
Storage before reconstitution
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Reconstitution
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
Storage after reconstitution
Up to two weeks at 4°C or three months at -20°C.
For more information, please refer to individual certificate of analysis for each product.
For research purposes only, not for human use
