Overview
Cat #: EK-115_KIT
Size: 8 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the TRPV1 Channel Activator Explorer Kit (#EK-115). The Explorer Kit contains TRPV1 activators, ideal for screening purposes.
For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background
TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid-gated, nonselective cation channel.
TRPV1 has many activators among them heat, protons, vanilloids like Capsaicin, Resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation1,2.
References
- Ross, R.A. et al. (2003) Br. J. Pharmacol. 140, 790.
- Tominaga, M. et al. (1998) Neuron 21, 531.
