Overview
Cat #: EK-114_KIT
Size: 14 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the TRPV1 Channel Modulator Explorer Kit (#EK-114). The Explorer Kit contains TRPV1 blockers and activators, ideal for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
A 784168 |
A-345 | 1 x 5 mg |
A-889425 |
A-195_1 mg | 1 x 1 mg |
AM 404 |
A-190_5 mg | 1 x 5 mg |
Arvanil |
A-335 | 1 x 10 mg |
BCTC |
B-110 | 1 x 10 mg |
Capsaicin |
C-125 | 1 x 50 mg |
Capsazepine |
C-120 | 1 x 5 mg |
LASSBio-1135 |
L-190 | 1 x 5 mg |
Nonivamide |
N-220 | 1 x 250 mg |
OLDA |
O-120 | 1 x 5 mg |
Olvanil |
O-115 | 1 x 5 mg |
Palvanil |
P-205 | 1 x 5 mg |
SB-366791 |
S-180 | 1 x 10 mg |
SB-705498 |
S-160 | 1 x 5 mg |
Scientific Background
Scientific Background
TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid gated, nonselective cation channel.
TRPV1 has many activators among them heat, protons, vanilloids like Capsaicin, Resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation1,2.
References
- Ross, R.A. et al. (2003) Br. J. Pharmacol. 140, 790.
- Tominaga, M. et al. (1998) Neuron 21, 531.
