Overview
Alternative Name Ambien, Zolpidemum, Lorex
Lyophilized Powder yes
Source Synthetic
MW: 307.39
Purity: >99%.
Effective concentration 0.1-100 nM.
Structure
Chemical name N,N-dimethyl-2-[6-methyl-2-(4-methylphenyl)imidazo[1,2-a]pyridin-3-yl]acetamide.
Molecular formula C19H21N3O.
CAS No.: 82626-48-0
PubChem CID 5732
Activity GABA(A) receptor agonist at the benzodiazepine site, potent and highly selective for α1-subunit-containing receptors (EC50 = 47.8 nM on α1β1γ2L)1.
References-Activity
- Horne, A.L. et. al. (1992) Br. J. Pharmacol. 107, 732.
Shipping and storage Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
Solubility Up to 100 mM in Ethanol and 50 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
Storage of solutions Up to four weeks at 4°C or three months at -20°C.
Our bioassay
Alomone Labs Zolpidem inhibits specific binding of Ro-15-1788 to cerebellum GABA(A) receptors.Percent inhibition of specific binding of 1 nM [3H] Ro-15-1788 to membranes from rat cerebellum, plotted against increasing concentrations of Zolpidem (#Z-100). Full inhibition is achieved at over 50 nM.
Target GABA(A) receptors
Lyophilized Powder
For research purposes only, not for human use
Last Update: 30/03/2021
Specifications
Citations
Citations
