Venomous creatures have a sophisticated mechanism for prey capture which includes a vast array of biologically active compounds, such as …
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Articles
The Role of p75NTR in Cancer
No generalizations about the role of this enigmatic receptor in cancer can be made. As in all other aspects of …
Continue readingKATP Channels: Linking Cell Metabolism to Cell Excitability
ATP-sensitive K+ channels (KATP channels) were described nearly 20 years ago in membrane patches of isolated ventricular myocytes. Since then, …
Continue readingInteractions of KCNE Auxiliary Subunits with KV and other Channels
KCNEs are integral membrane proteins that associate with and strongly modulate the activity of several ion channels. The different KCNE …
Continue readingCyclic Nucleotide-Regulated Ion Channels: From Light Sensing to Pace Keeping
The cyclic nucleotide-regulated ion channels are a heterogeneous superfamily of different ion channels that share common membrane topology and pore …
Continue readingThe Transient Receptor Potential (TRP) Ion Channels
TRP channels show diverse biophysical properties and gating mechanisms and were found to play an important role in sensory physiology, …
Continue readingMainstream- Fringe- and Patho- Physiology of Voltage Dependent Na+ (NaV) Channels
Voltage gated Na+ (NaV) channels mediate action potential genesis and propagation in most excitable cells. Other roles played by NaV …
Continue readingCa2+-Dependent K+ (KCa) Channels: At the Crossroads of Cell Metabolism
K+ channels are the largest and most diverse superfamily of ion channels. They are ubiquitously expressed in both excitatory and …
Continue readingTargeting Ion Channels in Living Cells
During the last few years there has been an increased focus on ion channel-related research in tissues and cells other …
Continue readingVoltage Dependent Ca2+ (CaV) Channels
In many physiological systems, voltage dependent Ca2+ (CaV) channels are the molecular link between cellular membrane potential and intracellular Ca2+ …
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